Metatine vapes are attempting to redraw the landscape of the vaping products market.  If you are an adult adult nicotine or tobacco users there are areas where the emergence of Metatine is nearly impossible miss. Specifically, those who live in markets where 21+ vapor consumers are being funneled back onto combustible cigarettes with capricious and ill-advised flavor bans. 

What is Metatine?

Metatine is described by its manufacturers as a synthetically derived molecule that is chemically distinct yet structurally similar to nicotine.

It is framed by critics and nicotine abstinence zealots as a synthetic nicotine analogue attempting to subvert the tobacco control act. Prohibitionists dead-set on denying adult vapers flavored products note that Metatine appears to be a synthetic analogue in the broader family of synthetic nicotine analogues and other vaping alkaloids.

Currently, the most common platform for consuming Metatine is as a liquid aerosol i.e., vape products that contain Metatine.

Metatine is Not Nicotine or a Tobacco Product

Metatine is not derived from tobacco. Metatine does not contain tobacco leaf or any material from the tobacco plant. Metatine is still an active ingredient product meant for 21+ adults who already consuming nicotine. Vaping.com does not want the business of adults who do not already consume nicotine.

We have robust age-verification and signature with delivery rules to prevent our products from being purchased by anyone under the age of 21. We view products like nicotine, patented Nixodine, and Metatine as alternatives for adult vapor consumers seeking smoke and ash free alternatives. 

Nicotine is addictive, and anything similar to nicotine should be approached with a strong sense of caution. The following article is not intended as medical advice or a substitute for treatment; if you have questions about use, talk with a healthcare professional. Consider contacting the Metatine website directly for specific questions. 

All products listed below intended for adults (21+) and may be habit forming. Refer to each manufacturer’s warnings. Local regulations are subject to change. 

Metatine Alternatives

Metatine is not alone on the market. Below are links to resources that examine Nixodine and NoNic6. 

Nixodine is a patented non-nicotine blend the provides a comparable experience to nicotine. Nixodine is designed specifically for vapor enthusiasts (21+), who are already using standard nicotine. NoNic products can be found in the Kumi family of vaping products. 

Related Products

• Nixodine Disposables
• Hot Box Elite 50K
• Lost Mary MT35K Nixodine
• Fifty Bar 20K Nixodine
• Nixodine Products

Related Articles

• What are Nixodine, NoNic6, and Metatine?
• Best Nixodine Disposable Vapes
• Fifty Bar Nixodine, SBX 25K Metatine and Juice Head iFlex Metadine Compared

 

Vapes Containing Metatine

Vapes that contain Metatine are marketed to consumers as providing the “similar satisfaction” or a “satisfying experience," when compared to traditional vape products or other forms of nicotine. They compete with NoNic6 and patented Nixodine. 

 

Metatine Vapes

There are several very capable models on the market, designed with the adult vapor consumer in mind. They are available in the best-selling selling flavors with adult vapers. There are plenty of fruit, tropical fruit, beverage, and icy sweet flavor fusions to choose from. 

• Spree Bar
• SBX 25K Metatine
• Juice Head Flex 50K Metatine
• Pachamama Plus Metatine E-Liquid 30ml

 

Spree Bar

The Spree Bar is a high-capacity, pre-filled vape pod kit that contains Metatine. It has a similar form factor and comparable functionality to a Vuse Alto or Juul but does not use traditional nicotine.

It is a much more advanced device than its Big Tobacco gas station rivals. It takes advantage of the myriad technological innovations that have occurred in the decade since those pod kits were launched. The Spree Bar's cost per puff, battery capacity, wattage, e-liquid capacity, flavor density, coil life and vapor production vastly outperform the Vuse Alto, Juul or MyBlu by any empirical measure. It is sold in popular flavors rather than the pretend tobacco notes that majority experienced adult vapers reject. There is no arguing with the American palate, which across the board embraces the same set of artificial fruit flavors in every consumable product. 

The Spree Bar is optimized for sale at convenience stores and gas stations, competing directly with traditional tobacco products although in in many areas products that contain Metatine avoid nicotine excise taxes.

Spree Bar Pod Kit

The most obvious advantage the Spree Bar has, apart from still being available in the flavors that adult user prefer, is that the capacity is 12ml. This is close 20x the size of Juul pod (0.7ml), and each pod holds as much e-liquid several boxes of Vuse Alto pods which have a capacity of 1.8ml. This equates to a puff count of an estimated 6000.

The Spree Bar pod kit includes both the battery and the pre-filled 12ml pod. The battery can be reused and pods purchased separately. 

Spree Bar Features

The Spree Bar has more than just a big pod going for it. Inside the pod is an advanced coil capable of handling the vast increase in longevity. The battery is also beefed up, at 650mAh it is comparable to a Geek Bar Pulse and has three times more battery capacity than a Juul. The 1.0ohm Mesh coil operates at 3.6V. No janky, proprietary charging cable or flimsy dock is required. This is USB-C charging,

Spree Bar products are powered by Betamax Hardware. The Spree Bar doesn't have quite the longevity of a disposable vape but does generate less waste as the battery is reused.

Spree Bar Specifications

• Prefilled Capacity: 12ml
• Powered By Metatine
• Battery Capacity: Removable 650mAh
• Max Puffs: 6000
• Metatine Strength: 5% (5000mg)
• Operation: Draw-Activated
• Heating Element: 1.0ohm Mesh Coil (3.6V)
• Charging: Type-C Port
• LED Indicator Light
• Powered by Betamax Hardware

Spree Bar Metatine Vape Flavors

Charlie's Chalk Dust and Pachamama were involved in the formulation of Spree Bar flavors. They have a great track record with e-liquids made using regular nicotine and nicotine salts. It is nicotine salts that the Spree Bar has benchmarked in order to create an experience akin to a disposable vape or pre-filled pod kit. 

Metatine products were created to be seamlessly integrated into existing vaping products. Apart from availability, it cannot be emphasized enough that their biggest advantage over pod kits is that they are available in the characterizing fruit and beverage flavors that the vast majority of adult vapers prefer. The fake tobacco flavors and faux-bacco notes sold by the tobacco industry in their dated e-cigarette designs not only cost far more for puff but are much less appealing to adult nicotine consumers.

This why cigarette sales increase when vape flavors are banned. More alarmingly, while nicotine consumption and vaping remain at historic lows, there is evidence that the much smaller percent of minors who continue to use nicotine are now more likely to smoke than they were before the flavor bans.  

As Metatine does not contain nicotine. Without the other volatile organic compounds found in burnt tobacco, there is almost no throat hit in these e-liquids. This is true even when compared to smooth nic salts rather a tobacco product.

• Strawberry Apple Melon: Strawberries, red apples, and juicy melon creating a flavorful masterpiece.
• Creamy Melon: A tropical fruit flavor mixed with a creamy finish to create an island beverage.
• Pineapple Coconut: A classic pineapple flavor and creamy coconut vape.
• Blood Orange Peach: Refreshing and tart citrus notes fused with juicy peach flavors.
• Watermelon Grapefruit: Pacha executes this strong watermelon and grapefruit flavor perfectly.
• Sweet Spearmint: The most popular vape pod flavor in history is mint and this one stacks up with the best.
• Blue Razz Ice: A tangy blue raspberry flavor with a refreshing, icy kick to keep you cool.
• Strawberry Mango: A harmonious blend of ripe strawberries and tropical mango, creating a paradise-like taste.

Pachamama Metatine E-Liquid 30ML

Pachamama E-Liquid made with Metatine™ is made with Metatine, a synthetically derived molecule that is structurally similar, but chemically different from other vaping alkaloids, Metatine is not made from, and does not contain, nicotine. In its natural state, Metatine is a colorless, odorless, liquid.

Pachamama e-liquids are formulated for use in conventional vape products.

Pachamama E-Liquid Specifications

• Capacity: 30ml Bottle
• Strengths: 25 and 50
• VG/PG Ratio: 50/50

 

Pachamama Metatine E-Liquid Flavors

Pachamama Metatine E-Liquids are sold in 25 and 50 strengths, which are intended to replicate the experience provided by popular nicotine salt strengths.

• Blueberry Watermelon Pomegranate: A balanced mix of ripe blueberry, juicy watermelon, and tart pomegranate—crisp and smooth.
• Lemon Apple Ice: Crisp lemon and red apple with a cool icy finish; smooth hit with Metatine Salt.
• Mango Lemon Lychee: Bright mango, zesty lemon, and floral lychee; smoother, more intense feel with Metatine Salt.
• Peach Pear Ice: A perfect blend of lush peach and pear with a refreshing chill and a clean, smooth finish.
• Pineapple Lush Ice: Juicy tropical pineapple followed by a frosty exhale—easy all-day fruit.
• Strawberry Kiwi Ice: Classic strawberry-kiwi with an icy twist for a smooth, satisfying puff.
• Strawberry Orange Banana: Ripe strawberry, tangy orange, and creamy banana in a bright, balanced trio.
• Strawberry Passionfruit Ice: Sweet strawberry and tangy passionfruit over ice; smooth and refreshing.

 

SBX 25K Metatine Vape

The SBX 25K Metatine is a big disposable vape with a modern design. The market of adult vapers has made their preference for this type of device very clear. Compared to a Spree Bar, it has more capacity, more features and more power on tap.

The SBX 25K Metatine has all the bells and whistles that veteran, 21+ vapor consumers want. This includes a bright display, three power modes, dual mesh coil, and adjustable airflow.

SBX 25K Metatine Specifications

• Capacity: 20ml
• Active Ingredient: Powered by Metatine
• Coil: Dual Mesh Coil Technology
• Display: Brilliant Color Display
• Airflow: Customizable Airflow Control
• 3 Power Modes
• Eco Mode: 15W/25K Puffs
• Boost Mode: 20W/20K Puffs
• X Mode: 25W/17K Puffs
• Charging: USB-C Rapid Recharging
• Battery: 1000mAh

SBX 25K Metatine Flavors

• Blue Razz Ice: Bold blue raspberry with a tangy pop and a crisp ice finish.
• Virginia Tobacco: Robust, familiar leaf character tailored for switchers from pod kits.
• Lemon Apple Ice: Juicy apple layered with a punch of tart lemon and a refreshing chill.
• Blueberry Burst: Ripe blueberry front and center—sweet, punchy, and to the point.
• Sweet Spearmint: Smooth spearmint sweetness with a cool breeze; clean and satisfying.
• Ripe Apple: Red apple done right—bright, juicy, and not the sour green kind.
• Grape Ice: Classic purple grape candy vibes cooled by a frosty exhale.
• Clear: Minimalist and mellow, keeping fruit and beverage notes out of the way.
• Mystic Ice: A chilled mystery-fruit medley with an extra-cold kick.
• Strawberry Kiwi: A balanced duo of ripe strawberry and vibrant kiwi, refreshingly familiar.

 

 

Juice Head iFlex 50K Metatine

The Juice Head iFlex holds no more e-liquid than the SBX 25K yet promises twice the number of puffs. Wrap your head around that. It does offer Ice Control, the ability to infused chill into each puff and also Strength Control, which appears to just be Boost Mode with a very dubious name.

The concept of Strength Control seems bring additional risk compared to just calling it Boost Control but there is no denying this is a powerful and impressive disposable vape. It is too bad that this "Strength Control" gimmick is catching on, as it will surely attractive negative attention. Multiple power mode and wattage control features have been a fixture of vaping for over a decade. 

Juice Head iFlex Metatine 50K Specifications

• Capacity: 18ml
• Active Ingredient: Powered By Metatine
• Features: Ice Control Technology
• Display: Mega 3D Display
• Modes: Strength Control
• Puff Count: Up to 50,000
• Charging: Type USB-C Rechargeable Battery

Juice Head iFlex Metatine 50K Flavors

• Miami Mint: Arctic-cool mint lifted by a squeeze of citrus; crisp and clean.
• Mexico Mango: Sun-ripened mango, dense and juicy with a soft candy finish.
• White Peach Raspberry: Lush white peach meets bright raspberry; gently tart and smooth.
• Raspberry Limeade: Zesty lime lemonade swirled with ripe raspberries; fizzy-drink vibes.
• Strawberry Banana: Creamy banana and sweet strawberry in a classic, comfort blend.
• Cherry Bomb: Bold black-cherry body with a sweet-tart spark.
• Sour Apple: Tangy green apple sharpened by an icy edge.
• Sour Fab: Playful sweet-and-sour fruit candy with a lively snap.
• Meta Moon: A cosmic mashup of papaya, strawberry-kiwi, and melon—mysterious yet refreshing.

 

Metatine Products

According to distributors and the manufacturer:

"Metatine does not contain nicotine, is not derived from tobacco, and is not a component or part of a tobacco product, it does not fall under the regulatory purview of the FDA’s Center for Tobacco Products.

Metatine does not meet the definition of nicotine as stated in the Family Smoking Prevention and Tobacco Control Act, is not a salt or complex of nicotine, and is not itself derived from nicotine or tobacco; accordingly, Metatine is not subject to FDA tobacco requirements. Metatine products are not required to obtain FDA premarket authorization (often known as a PMTA) required for new tobacco products, like e-cigarettes.

Metatine is not recognized as a drug in the official United States Pharmacopoeia and is not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. It is intended only as a satisfying alternative for adult tobacco users and vapers."

Metatine versus Synthetic Nicotine

Long-time vapers may remember the emergence of synthetic nicotine, which is still widely used in lozenges, gums, pouches, and some disposable vapes. These are not the same type of substances.

Metatine is chemically distinct while aiming to provide the satisfying experience associated with the traditional nicotine used in e-cigarettes and other nicotine products. Some customers online have suggested the user experience may be largely indistinguishable in conventional use.

From a safety lens, what matters is the toxicity profile. Even if a toxicity profile akin to nicotine eventually emerges, the presence of other substances, aerosols, and additives can change overall risk. Nixodine has been more forthcoming and more research will help debunk or pre-empt the myths and misinformation which are sure to flood social media channels and click-bait headlines for years to come. That the vaping industry is still fighting zombie myths like "Popcorn Lung", EVALI and a long-debunked vaping-heart disease studies should be a reminder of why there is no room for error in the arena of public opinion. 

Case for Metatine: Flavors in e-Cigarettes

Metatine serves one important purpose; to provide adult vapor consumers with the flavor profiles they prefer in a satisfying product. As flavor bans have been shown to increase cigarette sales, the discussion should be framed to acknowledge that there are consequences when adult consumers are funneled back onto combustible cigarettes in the pursuit of stronger regulations. Money from the tobacco industry and groups like the Orwellian-named Truth Initiative have flooded statehouses and Congress for years.

But at the end of the day, real adult nicotine consumers are forced to choose between abstinence, overpriced faux-tobacco pod kits, or combustible cigarettes when affordable and viable flavored e-cigarettes are decried as illicit, banned and criminalized. 

Using products containing Metatine does not convert vaping into a form of treatment; nicotine remains an addictive drug, and tobacco or nicotine analogues are not risk-free. 

Other Alternatives

Nixodine is a patented formula designed to provide similar to the same satisfaction as conventional nicotine. The manufacturer Bonguard Naturals has been conducting extensive studies to determine the health risks. Browse out Nixodine collections today.

USA-Built Fifty Bar 20K Nixodine

The USA-Assembled Fifty Bar 20K Nixodine is a great option if you want to enjoy the flavors of American master formulators in a device that is compact and powerful. Shop the amazing Beard Vape Co. inspired flavors and more classic disposable vape fare today. If you prefer classic disposables, Vaping.com also carries the complete line-up of Fifty Bar vapes.

Our Verdict

The future of substances and chemicals like Metatine are very much in the hands of the Food and Drug Administration (FDA). But if they are shown to have a toxicity profile similar to and superior to nicotine, could public health be served by opening up the market for adult nicotine consumers in pursuit of smoking prevention and tobacco cessation?